D-serine, a stimulator of activity at certain types of receptors in brain cells, has been tested as a new treatment for schizophrenia and bipolor disorder. D-serine is an amino acid found in the brain derived from Glycine.

Recent research suggests D-serine Supplements may be important for building up the brain circuitry that helps people filter out unnecessary information. D-serine helps activate NMDA receptors, communication ports found on excitaory neurons. NMDA receptors are known to be involved in changing neural connections as the brain learns and create memories. Scientists theorize that some schizophrenia symptoms may arise when these receptors are blocked from working or work only weakly.

Case Study

Akira Sawa, M.D. Ph. D and his colleagues found that adult mice that  developmentally displayed low levels of D-serine performed differently than healthy mice in a series of behavior experiments. The mice performed worse on some memory tests and tests on the brain’s ability to filter out distracting information.

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